My personal experience with Caron Simply Soft is that it looks worn very quickly, just because it is so soft it loses its integrity very quickly. I think the Bernat baby yarns are the same way. I don't think these yarns become fuzzy just because they are acrylic. There are certainly acrylics that wear better in my opinion.
I don't think baby powder would help; and I'd think it would just make your work dirty (I'm sort of OCD about keeping my hands clean while crocheting, no hand cream, eating etc.). Yarn gets fuzzy with wear, the more the fabric rubs against itself, you, the couch whatever, the fuzzier it gets.