Calcium D Glucarate (63 mg elemental calcium)500 mg

Heerdt AS, Young CW, Borgen PI. Calcium glucarate as a chemopreventive agent in breast cancer. Isr J Med Sci 1995;31:101-5. View abstract.

Source Naturals Calcium D-Glucarate 500mg, 120 Tablets

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  • TAG : calcium d glucarate 60 capsules $ 30 00 calcium d glucarate
  • Daily Nutrition In order to keep your body working at its’ peak, Calcium D Glucarate should be taken every day. The best protocol is to take 1 or 2 capsules with each meal. If you miss a dose during the day, do your best to take it at least twice daily with some sort of food or protein shake.

    Incredible Value - Buy the best Calcium D Glucarate supplement factory direct and qualify for FREE Shipping in Canada! Proteinco Canada’s commitment to you is in providing the highest quality supplements at the best possible price. One of the primary ways we accomplish this is by bringing this glucaric acid supplement directly to you rather than using retail outlets where the middleman drives up the price. Every order over $99 qualifies for FREE shipping which adds even more value.

    Calcium D-glucarate enhances the body’s natural defenses against environmental toxins and excess steroid hormones. Through the actions of its metabolite D-glucaro-1,4-lactone, calcium-d-glucarate indirectly favors glucuronidation, an important system that the body relies upon to deactivate and eliminate toxins and steroid hormones. Glucuronidation is a conjugation process through which potentially carcinogenic environmental toxins, such as polycyclic aromatic hydrocarbons and nitrosamines, and excess steroid hormones are neutralized. During glucuronidation, the enzyme glucuronosyl transferase catalyzes the conjugation of free carcinogens and steroid hormones to glucuronic acid. The resulting glucuronide-bound toxins and hormones can then be safely excreted in bile and urine. The body also deconjugates glucuronide-bound end products. The release of glucuronide-bound substances is beneficial in some circumstances, for example, when the excretion of steroid hormones is undesirable. Yet, the deconjugation process, which works via the enzyme beta-glucuronidase, can result in the re-release of harmful toxins back into the body. The benefits of calcium D-glucarate are realized indirectly through the action of its metabolite Dglucaro- 1,4-lactone, which inhibits the deconjugating enzyme beta-glucuronidase found in both blood and tissue. Inhibition of beta-glucuronidase causes a net increase in glucuronidation, and thereby enhances a primary detoxification pathway in the body. Animal studies have documented a decrease in B-glucuronidase activity in breast, liver, colon, skin, lung, and prostate tissue following oral administration of calcium Dglucarate. Once ingested, calcium D-glucarate is converted to Dglucaric acid in the presence of gastric HCl. The body normally maintains an equilibrium between D-glucaric acid and its two metabolites, D-glucaro-1,4-lactone and D-glucaro-6,3-lactone. Calcium D-glucarate provides a slow-release source of D-glucaro-1,4-lactone. When taken directly, D-glucaro- 1,4-lactone is metabolized quite quickly and is excreted from the body usually within 1-2 hours of its administration. Calcium D-glucarate, however, is metabolized slowly, remaining in the body for 5 or more hours after ingestion. This results in maintenance of stable levels of D-glucaro-1,4-lactone for long periods of time. D-glucaric acid is produced endogenously in small amounts. It is also present in some fruits and vegetables, including oranges, apples, grapefruit, broccoli and other cruciferous vegetables.

    A Calcium D Glucarate supplement comes from glucaric acid. Your body produces a small amount though not enough to combat increased environmental toxin exposure. Good food sources of glucaric acid include cruciferous vegetables ( i.e. the cabbage family veggies) like broccoli, brussels sprouts, kale, cabbages and bok choy. The benefits include liver detoxification of excess or used hormones like estrogen, T4 and androgens, as well as steroids, certain drugs, and many environmental toxins.

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  • Supplement Facts
    Serving Size: 1 Capsule
    Servings Per Container: 90
    Amount Per Serving %DV*
    Calcium D Glucarate 500mg **
    Other Ingredients: Gelatin, potassium bicarbonate, microcrystalline cellulose.

    Calcio D-Glucarato, Calcium Glucarate, Calcium-D Glucarate, Calcium-D-Glucarate, D-Glucarate (GA), D-glucaro-1,4-lactone (1,4 GL), Glucarate de Calcium.

Estrogen Dominance: DIM and Calcium D Glucarate Reviews

I would love a reply to this please:.. I was having breast tenderness and what I am sure is xenoestrogens/estrogen dominance symptoms.. I took the calcium d glucarate in the middle of the night and woke up with no more breast tenderness. I was really surprised how fast it worked.. for the following weeks I took it and it really made a difference in the way I was feeling. I am 47 and do supplement with the progesterone cream. When I do this, 3 days in, I start feeling like it is raising my estrogen as well and when that happens the cream stops working. The Calcium d glucarate allowed the progesterone to do it's job.. Then my period came and I continued to take the calcium d and it caused pains everywhere. I stopped it, unsure if it was the calcium d.. After my period ended and after ovulation I started it up again only to have it cause my entire body to have muscle pains again..